Methotrexate or Rheumatrex as it also known, is classified as a chemotherapeutic agent and comes with a long list of side-effects which those who are considering taking it should be aware of before making any final decisions either way. There are other drugs for chemotherapy, though most of them tend to cause tinnitus as a side-effect, at least in some people. These drugs include Plantinol, Parlodel, Velban, Oncovin, and more.
Some of the more common side-effects of this powerful drug include severe toxicity of the liver, upset stomach, low white counts, and mouth sores. While some people have had even more severe reactions, these are the most common. Tinnitus is also considered to be a semi-common side-effect of taking this drug, though not everyone who is prescribed it will experience this problem.
Other side-effects which you might expect to have problems with after taking Methotrexate include itchy skin, rashes, hair loss, and dizziness. Through the numerous trials and studies that have been done involving this chemotherapy drug, only a small percentage of people involved in them experienced problems with tinnitus. One of the most serious side-effects that this drug produces involves a toxic effect on the liver.
Usually when someone develops tinnitus as the result of taking a certain medication, they are said to have experienced an ototoxic effect. There are certain medications which are ototoxic, including various antibiotics, diuretics, antidepressants, and drugs like this one which are prescribed to cancer patients for chemotherapy.
Most of the people who are prescribed Methotrexate take it in high doses because their cancer has progressed to a certain stage and requires aggressive treatment. Those who are pregnancy will want to avoid taking this drug and perhaps those who have a history of inner ear problems such as tinnitus as it could bring back or exacerbate this condition.
